How long does it take to start working?

From the moment you apply Viroxyn Professional Use it begins the healing. The benzocaine will relieve you from pain initially, allowing the medicine to be applied aggressively and effectively. Cold sore pain is gone within an hour for most patients.

How many vials are needed to heal a cold sore?

Just one dose of Viroxyn Professional Use is needed for a single outbreak.

Do these need to be stored in a refrigerator?

No, they just need to be stored in a dry place where they cannot be stepped on or broken.

Can this be billed through insurance? What Code do I use?


Yes, the application can be applied in-office by a member of the dental team, and can be billed through insurance as a palliative (emergency) treatment of dental pain, code D9110.

Do you treat the patient or do they apply it themselves?

It is completely up to the dental team. We recommend the dental professional applying Viroxyn Professional Use in-office, and then either sending them with an extra vial for a future outbreak, or selling them a package of their own for future use.

Do you have information I can give to my patients about Viroxyn Professional Use?

Yes, we offer brochures you can give to your patients, as well as set out in your waiting room to educate your patients about the cold sore virus.

How long does it take to ship?

Your order will be shipped the same day that you order it, and standard shipping is two-to-three days. It is sent via USPS Priority Mail. Overnight shipping is an option for an additional fee.

What is the shelf life of Viroxyn Professional Use?

Viroxyn Professional Use can be stored in a dry place for up to three years.

Is this available in stores?

No, Viroxyn Professional Use is only available through a dental professional.

Can I use this product on a child?

Yes, Viroxyn Professional Use can be used on any child two years of age and older.

What is/are the active ingredient(s) in Viroxyn and how does it/they work?

Benzocaine is present to deaden the treatment site prior to actual treatment. This is to dull the sting from the alcohol base. Benzalkonium chloride is the germicidal ingredient and it acts to disrupt the lipid envelope of the cold sore virus.

Can I write a prescription for Viroxyn Professional Use for my patient to fill at the drug store?

Viroxyn Professional Use is only available from participating dentists who dispense it to their patients while providing them with additional information on the cold sore virus and how it is similar and different from members of its viral family.

How is Viroxyn different from Acyclovir and other nucleoside drugs?

The nucleoside drugs offer the cold sore virus a defective DNA building block. This is a “numbers game” as there is plenty of good Human DNA building block material available. In some people, the cold sore virus can and has mutated to be unaffected by the nucleoside drugs. Viroxyn acts to disrupt the lipid envelope of the cold sore virus and thus render it inactive. The cold sore virus cannot mutate to resist the active ingredient in Viroxyn.

Can I read about Viroxyn in the peer-reviewed dental literature?

Viroxyn is taught as a “standard of care” option in several dental textbooks and journal articles.1,2,3,4

Are there any clinical studies published in the dental literature?

There is a study showing a head to head matchup between Viroxyn and Abreva using untreated cold sores as a control.4 In this study, the untreated cold sores healed in a median 11.0 days, Abreva helped some with a median time to healing of 7.0 days and Viroxyn healed cold sores in a median 3.0 days. (n = 180)

  1. Essentials of Oral Medicine, Silverman, Eversole, Truelove, 2001 BC Decker, Hamilton, ON Table 13-2 p.122
  2. Drug Information Handbook for Dentistry, 17th Ed. 2011, Lexicomp, Hudson, OH p. 1990
  3. Spivakovsky S, Kerr R, Ship J, Diagnosis and Management of Recurrent Aphthous Ulcers and Recurrent Oral Herpes, Journal of Practical Hygiene, 2005, 14(6) p 11.
  4. McCarthy J, Browning W, Teerlink C, Veit G, Treatment of Herpes Labialis: Comparison of Two OTC Drugs and Untreated Controls, Journal of Esthetic and Restorative Dentistry, 2012, 24(2) p103–109.